Searchable abstracts of presentations at key conferences in endocrinology

ea0041gp152 | Pituitary - Clinical | ECE2016

Effects of hydrocortisone substitution on blood pressure – results from an RCT

Buning Jorien Werumeus , van Faassen Martijn , Brummelman Pauline , Dullaart Robin P F , van den Berg Gerrit , van der Klauw Melanie M , Kerstens Michiel N , Kobold Anneke C Muller , Kema Ido P , Wolffenbuttel Bruce H R , van Beek Andre P

Background: Patients with secondary adrenal insufficiency show increased risk of cardiovascular disease. Higher doses of glucocorticoid replacement are related to an unfavourable metabolic profile. In the absence of randomized controlled trials assessing the effect of hydrocortisone dose on haemodynamics and blood pressure regulation, we determined effects of a higher vs a lower glucocorticoid replacement dose on blood pressure, the renin-angiotensin-aldosterone system (RAAS) ...

ea0056oc13.1 | The curious case of growth hormone | ECE2018

Postoperative use of somatostatin analogs and mortality in patients with acromegaly

Postma Mark R , Wolters Thalijn LC , van den Berg Gerrit , van Herwaarden Antonius E , Kobold Anneke C Muller , Sluiter Wim J , Wagenmakers Margreet A , van den Bergh Alfons CM , Wolffenbuttel Bruce HR , Hermus Ad RMM , Netea-Maier Romana T , van Beek Andre P

Objective: To assess the effect of somatostatin analogs (SSTA) on mortality in relation to metabolic control of acromegaly after pituitary surgery.Design: A retrospective study in two large tertiary referral centers in The Netherlands.Patients and methods: Three hundred and nineteen patients with acromegaly in whom pituitary surgery was performed as primary therapy between January 1980 and July 2017 were included (total follow-up: ...